2025, Vol. 7, Issue 2, Part B
Cell-based therapy for chronic non-healing ulcers: A case study of venous ulcer
Author(s): Prujal Parekh, Kranti Vora, Sanjana Shah, Shashank Patel, Senthilkumar Natesan and Pankaj Modi
Abstract:
Venous leg ulcers (VLUs), sometimes referred to as varicose ulcers, account for around 70 percent of chronic leg ulcers globally and are among the most common non-healing ulcers. Venous leg ulcer, primarily caused by insufficient venous circulation, are mostly found in older people and people with varicose veins. VLUs also cause substantial socioeconomic difficulties as a result of pain, discharge from the wound and chronic nature of the ulcer. As there is no effective treatment, the medical expenses mount as months passes by. This study highlights use of the autologous collagen-based gel treatment to cure persistent VLUs. This novel therapy was used to treat two male patients with non-healing venous foot ulcers who showed significant wound reductions of 83% and 93%. By applying a gel made from the patient's own blood to the wound site, the treatment reduces the risk of infection while encouraging the formation of granulation and epithelial tissue leading to healing. This case study indicates that VLU patients unresponsive to conventional treatment may benefit from this cell-based therapy.
DOI: 10.22271/27081494.2025.v7.i2b.205
Pages: 79-82 | Views: 278 | Downloads: 138
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